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Research progress in pathogenic genes of hereditary non-syndromic mid-frequency deafness
Wenjun Xia,Fei Liu,Duan Ma
Frontiers of Medicine 2016, Volume 10, Issue 2, Pages 137-142 doi: 10.1007/s11684-016-0449-8
Keywords: hereditary non-syndromic hearing loss mid-frequency hearing loss deafness genes
Ionically Imprinting-Based Copper (Ⅱ) Label-Free Detection for Preventing Hearing Loss Article
Huan Wang, Hui Zhang, Xiaoli Zhang, Hong Chen, Ling Lu, Renjie Chai
Engineering doi: 10.1016/j.eng.2023.09.001
Keywords: Structural color Microfluidics Ionic imprinting Label-free detection Hearing loss
Frontiers of Medicine doi: 10.1007/s11684-023-1006-x
Keywords: neurodevelopmental disorder autosomal recessive intellectual disability consanguinity spastic paraplegia hearingloss TMEM141
Alternative splicing of inner-ear-expressed genes
Yanfei Wang,Yueyue Liu,Hongyun Nie,Xin Ma,Zhigang Xu
Frontiers of Medicine 2016, Volume 10, Issue 3, Pages 250-257 doi: 10.1007/s11684-016-0454-y
Keywords: alternative splicing inner ear hearing loss hair cells
Loss of liver kinase B1 causes planar polarity defects in cochlear hair cells in mice
Yuqin Men,Aizhen Zhang,Liwen Zhang,Yecheng Jin,Zhishuo Wang,Jing Zhao,Xiaolin Yu,Jian Zhang,Jiangang Gao
Frontiers of Medicine 2016, Volume 10, Issue 4, Pages 481-489 doi: 10.1007/s11684-016-0494-3
The tumor suppressor gene liver kinase B1 (LKB1), also called STK11, encodes a serine/threonine kinase. LKB1 plays crucial roles in cell differentiation, proliferation, and polarity. In this study, LKB1 conditional knockout mice (LKB1Pax2 CKO mice) were generated using Pax2-Cre mice to investigate the function of LKB1 in inner ear hair cells during early embryonic period. LKB1Pax2 CKO mice died perinatally. Immunofluorescence and scanning electron microscopy revealed that stereociliary bundles in LKB1Pax2 CKO mice were clustered and misoriented, respectively. Moreover, ectopic distribution of kinocilium bundles resulting from abnormal migration of kinocilium was observed in the mutant mice. The orientation of stereociliary bundles and the migration of kinocilia are critical indicators of planar cell polarity (PCP) of hair cells. LKB1 deficiency in LKB1Pax2 CKO mice thus disrupted hair cell planar polarity during embryonic development. Our results suggest that LKB1 is required in PCP formation in cochlear hair cells in mice.
Keywords: LKB1 stereociliary bundles kinocilium planar cell polarity hearing mice
Power fluctuation and power loss of wind turbines due to wind shear and tower shadow
Binrong WEN, Sha WEI, Kexiang WEI, Wenxian YANG, Zhike PENG, Fulei CHU
Frontiers of Mechanical Engineering 2017, Volume 12, Issue 3, Pages 321-332 doi: 10.1007/s11465-017-0434-1
Keywords: wind turbine wind shear tower shadow power fluctuation power loss
Turnover and loss of nitrogenous compounds during composting of food wastes
YANG Yanmei, ZHANG Xiangfeng, YANG Zhifeng, XI Beidou, LIU Hongliang
Frontiers of Environmental Science & Engineering 2008, Volume 2, Issue 2, Pages 251-256 doi: 10.1007/s11783-008-0042-8
Winner determination problem with loss-averse buyers in reverse auctions
Xiaohu QIAN, Min HUANG, Yangyang YU, Xingwei WANG
Frontiers of Engineering Management 2017, Volume 4, Issue 2, Pages 212-220 doi: 10.15302/J-FEM-2017019
Keywords: reverse auction loss aversion winner determination improved ant colony algorithm
New US Rules Promise to Unlock Hearing Aid Availability
Mitch Leslie
Engineering 2022, Volume 14, Issue 7, Pages 7-9 doi: 10.1016/j.eng.2022.05.008
A novel energy loss model and optimization design of the coin chute flection curve
Qinghua LIANG, Jinqiu MO, Weizhong GUO
Frontiers of Mechanical Engineering 2012, Volume 7, Issue 1, Pages 38-46 doi: 10.1007/s11465-012-0311-x
In this paper, we propose a novel design model based on the energy loss of the coin (ELM model) toTwo different kinds of energy loss models are analyzed according to dynamic characteristics of the coinpoints and end points derivatives as inputs, and the curve model is governed and affected by energy lossequations, allowing to minimize the total energy loss before the coin arrives at the detecting position, thus to reduce the energy loss and collisions between the coin and the flection, thus to improve the
Keywords: flection curve B-spline energy loss model (ELM model) optimization design
K Sathish KUMAR,S NAVEEN
Frontiers in Energy 2014, Volume 8, Issue 4, Pages 434-442 doi: 10.1007/s11708-014-0313-y
Keywords: distribution system reconfiguration (DFR) power loss reduction catfish particle swarm optimization (catfish
Yifu ZHANG,Hongwen LI,Jin HE,Qingjie WANG,Ying CHEN,Wanzhi CHEN,Shaochun MA
Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 2, Pages 161-170 doi: 10.15302/J-FASE-2016104
Keywords: infiltration initial soil water content rainfall simulation soil loss straw mulching
Erhui GUO,Liding CHEN,Ranhao SUN,Zhaoming WANG
Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 2, Pages 279-287 doi: 10.1007/s11783-014-0667-8
Keywords: riparian vegetation patterns soil nutrient distribution nutrient loss management
Frontiers of Medicine 2021, Volume 15, Issue 3, Pages 460-471 doi: 10.1007/s11684-021-0861-6
Keywords: low-carbohydrate diet obesity nonalcoholic fatty liver disease continuous glucose monitoring mean sensor glucose
A novel approach to minimizing material loss for computer numerical control flank-regrinding of worn
Frontiers of Mechanical Engineering 2023, Volume 18, Issue 3, doi: 10.1007/s11465-023-0757-z
Keywords: flank-regrinding worn end mill wheel position and orientation material loss over-cut
Title Author Date Type Operation
Research progress in pathogenic genes of hereditary non-syndromic mid-frequency deafness
Wenjun Xia,Fei Liu,Duan Ma
Journal Article
Ionically Imprinting-Based Copper (Ⅱ) Label-Free Detection for Preventing Hearing Loss
Huan Wang, Hui Zhang, Xiaoli Zhang, Hong Chen, Ling Lu, Renjie Chai
Journal Article
Panoramic variation analysis of a family with neurodevelopmental disorders caused by biallelic loss-of-function
Journal Article
Alternative splicing of inner-ear-expressed genes
Yanfei Wang,Yueyue Liu,Hongyun Nie,Xin Ma,Zhigang Xu
Journal Article
Loss of liver kinase B1 causes planar polarity defects in cochlear hair cells in mice
Yuqin Men,Aizhen Zhang,Liwen Zhang,Yecheng Jin,Zhishuo Wang,Jing Zhao,Xiaolin Yu,Jian Zhang,Jiangang Gao
Journal Article
Power fluctuation and power loss of wind turbines due to wind shear and tower shadow
Binrong WEN, Sha WEI, Kexiang WEI, Wenxian YANG, Zhike PENG, Fulei CHU
Journal Article
Turnover and loss of nitrogenous compounds during composting of food wastes
YANG Yanmei, ZHANG Xiangfeng, YANG Zhifeng, XI Beidou, LIU Hongliang
Journal Article
Winner determination problem with loss-averse buyers in reverse auctions
Xiaohu QIAN, Min HUANG, Yangyang YU, Xingwei WANG
Journal Article
A novel energy loss model and optimization design of the coin chute flection curve
Qinghua LIANG, Jinqiu MO, Weizhong GUO
Journal Article
Power system reconfiguration and loss minimization for a distribution systems using “Catfish PSO” algorithm
K Sathish KUMAR,S NAVEEN
Journal Article
Effect of mulching with maize straw on water infiltration and soil loss at different initial soil moistures
Yifu ZHANG,Hongwen LI,Jin HE,Qingjie WANG,Ying CHEN,Wanzhi CHEN,Shaochun MA
Journal Article
Effects of riparian vegetation patterns on the distribution and potential loss of soil nutrients: a case
Erhui GUO,Liding CHEN,Ranhao SUN,Zhaoming WANG
Journal Article
Low-carbohydrate diets lead to greater weight loss and better glucose homeostasis than exercise: a randomized
Journal Article